· Frabone®’s inspiration came from the Haversian canals in compact bones.
-These canals, 50 – 200 μm in diameter, serve as the conduits for the blood vessels which supplies the necessary nourishment for bone growth and metabolism of the compact bones.
-The oriented arrangement of the Haversian canals into osteons also contribute to the bones’ mechanical strength.
· Frabone®’s micro-channels mimic the Haversian system of human bones.
-The microchannels and inter-granular spaces allow the efficient formation of blood vessels and penetration of osteoblasts that are the precursors of new bone formation as well as osteoclasts to aid in the resorption of the implanted materials and bone remodeling.
-This bone mimicking design of Frabone® was achieved through the patented fabrication technology of multi-pass extrusion of bioceramics.
(The patent is registered in Korea while in process in the US and EU)
Upon injury, bone has impressive self-healing capacity.